Q-STAIN X (QSXTM)-Enh PRAME (Clone R1009) is a rabbit monoclonal antibody is intended for laboratory use to qualitatively identify by light microscopy the presence of PRAME protein in sections of formalin-fixed, paraffin-embedded (FFPE) and/or fresh frozen tissues using immunohistochemistry (IHC) test methods. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests and proper controls interpreted by a qualified pathologist and/or physician. This conjugated antibody has been pre-diluted and optimized for IHC use without further dilution.
Summary and Explanation:
QSX-Enh PRAME is a ready-to-use rabbit monoclonal antibody reagent (clone R1009). Preferentially expressed Antigen in Melanoma (PRAME) is encoded by the PRAME gene and has a molecular weight of approximately 57 kDa. PRAME is predominantly expressed in human melanomas and recognized by cytolytic T lymphocytes. The antibody may also have a role in acute leukemias and in preventing the growth or metastasis of breast cancer cells. See Q-STAIN X User’s Guide to learn more about test protocols.
