Q-STAIN (QSXTM)-Enh CEA (Anti-Human Carcinoembryonic Antigen) antibody is intended for laboratory use to qualitatively identify by light microscopy the presence of CEA molecules in sections of formalin-fixed, paraffin-embedded tissue sections or frozen tissues using immunohistochemistry (IHC) test methods. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist/physician. These reagents have been formulated to ready-to-use concentration and optimized for IHC on specific tissue application use without further dilution.
Summary and Explanation:
QSX-Enh CEA is a ready-to-use mouse monoclonal antibody reagent (clone C135). CEA refers to Carcinoembryonic Antigen and is also known as CD66e. It expresses in nearly 100% colorectal cancers (CRC) and is a biomarker commonly used in a colorectal cancer IHC antibody panel. CEA expression is seen in adenocarcinomas from the lung, colon, and stomach. The marker is often used with other markers to help distinguish between adenocarcinoma and epithelioid malignant mesotheliomas.1,2 See Q-STAIN X User’s Guide to learn more about test protocols.