Q-STAIN (QSXTM)-Enh SMMS-1 antibody (anti- human smooth muscle myosin heavy chain, SMMHC) is intended for laboratory use to qualitatively identify by light microscopy the presence of the presence of smooth muscle myosin heavy chain in sections of formalin-fixed, paraffin-embedded tissue sections or frozen tissues using immunohistochemistry (IHC) test methods. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist/physician. These reagents have been formulated to ready-to-use concentration and optimized for IHC on specific tissue application use without further dilution.
Summary and Explanation:
QSX-Enh SMMS-1 is a ready-to-use mouse monoclonal antibody reagent (clone SMMS-1). The SMMS-1 antibody reacts with human visceral and vascular smooth muscle cells. The antibody also recognizes human myoepithelial cells. IHC staining with SMMS-1 antibody is very helpful in distinguishing benign sclerosing breast lesions and carcinoma in situ from infiltrating breast carcinoma.1,2 See Q-STAIN X User’s Guide to learn more about test protocols.
